Flagel Laboratory MBNI G059
Our research focuses on understanding the genetic, environmental, and neurobiological factors that contribute to individual differences in reward learning and susceptibility to mental illness. We use behavioral, pharmacological, and chemogenetic tools to understand the biological basis of motivated behavior. The equipment we employ in our work includes but not limited to: operant training boxes, centrifuges, hot plates, microscopes, freezers, shaker plates and fume hoods. Waste generated in our lab is disposed of adhering to OSEH guidelines.
“I am so glad that the University of Michigan has a sustainable lab program and that I can contribute to its missions of waste reduction and decreasing our carbon footprint. This program has provided opportunities to recycle lab supplies, share equipment, and reuse chemicals. We only have one planet and we need to all we can to protect it.” Marin Klumpner, Lab Manager
Pennathur Laboratory Brehm 5450
Our research focused on the applications of biological mass spectrometry in disease pathogenesis. A major focus of the lab has been to define the role of oxidative stress on disease pathogenesis and complications. We have utilized mass spectrometry to identify key protein and metabolite alterations in disease states and tested the hypothesis whether these alterations predict complications in animal models and humans. Our strategy has been to develop analytical techniques in animal models and validate these markers in humans and then interrogating the animal model for biological pathway relevance. Recent extension of this work has included targeted as well as unbiased metabolomic and proteomic profiling. Waste generated in our lab is disposed of using OSEH guidelines.
“This program has helped us identify many new ways to operate sustainably. We're able to recycle much more, both chemicals and waste, and reduce our energy use, using the info provided by the program. Everyone in the lab is motivated to function as sustainably as possible, and the Sustainable Lab program has been integral to our efforts.”
-- Nancy Roeser, Lab Manager
Montgomery Laboratory Chemistry 3724-3728
Our research focuses on the discovery of new transition metal-catalyzed reactions, the development of useful synthetic methods, the application of these new reactions in complex molecule synthesis, and mechanistic studies designed to understand the new processes developed in our laboratories. Common equipment used on a daily basis include NMR, MS, GC/MS, GC/FID, HPLC, gloveboxes, rotary evaporators, kugelrohr, Biotage automated chromatography, and vacuum lines. Common techniques include reaction set-up, chromatography, distillations, extractions and spectroscopic analysis. Solid and hazardous waste generated in our lab is disposed of adhering to U-M OSEH guidelines.
“We are very happy to participate in the Sustainable Lab program to work towards making our lab more eco-friendly. Now more than ever we are dedicated to using green chemistry practices and reducing energy consumption whenever possible to make sure that we do our part in helping our environment. We highly encourage other laboratories at Michigan to take advantage of this opportunity and to be a part of planet blue!”
-- Jessica Stachowski, Lab Manager
Tropical Climbing Plants Laboratory Ruthven 1047
Our research involves morphological analysis of climbing plant species, seed germination, stem re-sprouting/re-rooting capability trials, and computer analysis of all data. Our specimens come from Amazonian Ecuador, Peru, and Brazil where we carry out biodiversity and ecological research on the dominant species of moist tropical forest. Specimens are dried using standard drying ovens and plant presses, and housed in sealed herbarium cabinets. Waste is rarely generated in our lab. Rare solid and liquid waste generated in our lab is disposed of adhering to U-M OSEH guidelines.
“The Sustainable Lab program staff were very helpful with respect to increasing our awareness of safe and sustainable lab practices and evaluating our current use of resources. With their assistance we have updated our energy use to eliminate connections that are not needed, and we have eliminated mercury thermometers in the lab. We have also updated our recycling practices and posted signs about recycling and composting in the lab. We are committed to purchasing eco-friendly products whenever possible. These changes were very easy to adopt, and we are happy to participate in this program and help U-M reach its campus-wide sustainability goals.”
-- Prof. Robyn Burnham, PI
Denver Laboratory Kraus 3071, 3077
We study hormone action during animal development, with emphasis on the nervous system. Our molecular and cellular studies are integrated with organismic level questions of physiological adaptation to environmental change and the evolution of vertebrate neuroendocrine systems.Waste generated in our lab is disposed of using OSEH guidelines.
“Denver lab is very happy to be the part of Sustainable Lab program. We eliminated the use of ethidium bromide by making use of safer alternatives. We now recycle all empty pipette tip boxes and clean media bottles. The Chemical Reuse program has us allowed us to procure chemicals, etc. at no cost. We also keep equipment that is not being used daily unplugged. This is a great program.”
-- Arasakumar Subramani, Lab Manager
Penner-Hahn Laboratory Chemistry Rooms 4205, 4213, 4208, & 4211
Our group is interested in the spectroscopic investigation of metal site structure in bioinorganic systems. We focus our studies in understanding the detailed mechanism of enzymes with Zn as an active site. It is estimated that as many as one-third of all proteins are metalloproteins. We are engaged in attempting to identify and characterize the metal bonding sites in these proteins. We develop new techniques in X-Ray spectroscopy to determine the local side structure of metals ions in the biological systems. Our research also involves studying the distribution of metals in red blood cells infected with malaria and the distribution of metals in the hippocampus. We do not generate hazardous waste. Other solid waste generated is recycled or disposed of as trash.
“Using the Sustainable Lab program has been highly beneficial to our lab. We powered down many equipment that is not being used on a regular basis. Many recycling programs have been initiated as part of this program. We are glad that our lab is recognized through this unique program.”
-- Dr. Aniruddha Deb, Lab Manager
O'Brien Laboratory 4200 MSRB III
Our research interests focus on elucidating the catalytic mechanisms of proteins involved in DNA repair, with current focus on ligases and alkylation repair pathways. We employ a variety of electrophoresis and fluorescence techniques in addition to mutation assays in biological systems. Waste generated in our lab is disposed of adhering to OSEH guidelines.
Participation in the Sustainable Lab Recognition Program has improved our awareness of the environmental impact of our research. It has helped us to develop energy-saving practices, reduced our hazardous waste generation, and introduced us to various recycling streams. Michael Baldwin, lab manager
Bridges Laboratory SPH II 6041, 7065, & 7616
We use a variety of cellular and molecular techniques including protein, metabolite mRNA analyses to address changes in physiology related to obesity. This involves a variety of mouse, rat and fruit fly models as well as cell culture systems. We have several pieces of equipment to assist in these studies including centrifuges, refrigerators, freezer, thermal cyclers, a magnetic resonance body composition analyzer and standard molecular biology equipment. The waste generated in our lab is disposed of adhering to U-M OSEH guidelines.
“Guided by the Sustainable Lab Program staff, we have taken several steps to establish our lab space to create a sustainable and safe environment for our work. Using the ChEM Reuse Program in particular has been a great way to reuse chemicals and equipment while saving some money. We have been able to eliminate ethidium bromide, reduce methanol waste and recycle a large amount of our waste. We have also become more cognizant of our electricity usage and purchasing habits.”
-- Dr. Dave Bridges, Principal Investigator
Dawid Laboratory MSRB I 7500& 7504
We are interested in understanding the bacterial factors that promote successful colonization of Streptococcus pneumoniae, a leading cause of disease in people of all ages. This organism spends majority of its life in the polymicrobial environment of the nasopharynx where it is exposed to attack by the host immune system as well as by other inhabiting or invading organisms. We are interested in gaining a better understanding of inter-bacterial interactions and how these interplay with bacterial adaptation. This understanding may help us to better predict the outcome of targeted vaccination and can lead to inventive strategies to treat or prevent pneumococcal infection. Waste generated in our lab is disposed of adhering to OSEH guidelines.
“Reduce, reuse, and recycle” are goals in my daily life. I am glad that I can promote and implement these in my lab by joining the Sustainable Lab Program. I have learned more strategies of becoming an environmentally friendly research lab. Let’s all become sustainability ambassadors for our planet. Winnie Wholey, Manager
Ellingrod Laboratory College of Pharmacy 2059
Our research interests are primarily related to improving the safety of mental health pharmacotherapy through precision medicine research. We have been focusing on the role of pharmacogenetically regulated folate metabolism and its relationship to metabolic syndrome and endothelial dysfunction seen with antipsychotic use in patients with schizophrenia or bipolar disorder. Recent work has incorporated methylation, microbiome, and metabolomic data to further our understanding of the relationship between medication use and cardiovascular disease risk in these populations. We employ molecular biology techniques in our work. The waste generated in our lab is disposed of adhering to U-M OSEH guidelines.
“The Sustainable Lab program staff were very helpful with respect to increasing our awareness of safe and sustainable lab practices. With their assistance we have eliminated ethidium bromide and switched to the GelRed dye alternative. We have also expanded our recycling practices, committed to purchasing eco-friendly products whenever possible, and turning off and unplugging unused devices to reduce our energy consumption. These changes were very easy to adopt, and we are happy to participate in this program and help U-M reach its campus-wide sustainability goals.”
-- Kristen Ward, Fellow