Day Laboratory NCRC B520 Rooms 1408 & 1409
The main focus of our research is to identify better agents for the treatment of patients diagnosed with metastatic bladder cancer. Currently, we are working in the area of natural products to identify chemicals from plants that have potent anti-cancer properties. We employ cellular and molecular biology techniques in our research. Hazardous and non-hazardous waste generated in our lab is disposed of adhering to U-M EHS guidelines.
In the Day lab we realize the importance of “reduce, reuse, and recycle” so we make this a daily goal. We are happy to promote and implement this theme in our lab and have now joined the Sustainable Lab Program. By joining, this has increased our awareness and helped us improve our strategies to become even more environmentally friendly in the work place and in our homes. Let’s all become sustainability ambassadors for our one and only planet.
Kathleen Day, Manager
Sun Laboratory NCRC B520
Our lab’s research focuses on drug discovery to inhibit cancer stem cells and nanomedicine for cancer therapeutics. We also study drug delivery and bioequivalence for drugs, and are conducting several clinical studies for drug dissolution in GI tract sponsored by the Food and Drug Administration. Dr. Sun serves as the Director of Pharmacokinetics (PK) Core in the University of Michigan. The PK Core mainly works on: A) To support preclinical pharmacokinetics and metabolism for lead compound selection and dose regimen optimization, which enhances drug discovery and development. B) To support clinical pharmacokinetics and optimize dose regimen in clinical studies. Waste generated in our lab is disposed of using OSEH guidelines.
“Reduce, Reuse and Recycle. Sun lab has taken every possible measure for a better practice at research. We minimize the use of energy and hazardous materials; we eliminate the use of ethidium bromide, mercury thermometers and radioactive materials; we reuse and recycle plastic, Styrofoam, and carton boxes. Thanks to the UM Sustainable Lab Recognition Program. It not only helps us work in a safer workplace, but also helps keep our planet clean.”
-- Dr. Jinhui Liao, Lab Manager
Debiec Laboratory MBNI 2024
Our research focuses on early life learning via fear conditioning and its effects on health and disease. Our lab conducts behavioral testing using primarily an odor distributor, electric shock stimulator, and a computer, and also include perfusions and immunohistochemistry in some experiments. Equipment that is used consists of but is not limited to a vortex mixer, ethovision, cryostat, and microcentrifuge. Waste generated in our lab is disposed of adhering to OSEH guidelines.
“Our lab is very pleased to have become part of the sustainable lab program, participating in recycling programs and equipment sharing where able. We were thrilled to learn of a program dedicated to using our energy resources more efficiently, especially at such a large university. Through the sustainability program we have learned about reducing chemical waste and the minimal effects of raising the temperature of our freezer to -70 degrees C. Moving forward, we will keep up to date with sustainable news and try to implement changes into our experimental procedures. We are invested in decreasing lab waste and continuing in the program in order prioritize the planet’s resources.” Joanna Hider, Lab Manager
Flagel Laboratory MBNI G059
Our research focuses on understanding the genetic, environmental, and neurobiological factors that contribute to individual differences in reward learning and susceptibility to mental illness. We use behavioral, pharmacological, and chemogenetic tools to understand the biological basis of motivated behavior. The equipment we employ in our work includes but not limited to: operant training boxes, centrifuges, hot plates, microscopes, freezers, shaker plates and fume hoods. Waste generated in our lab is disposed of adhering to OSEH guidelines.
“I am so glad that the University of Michigan has a sustainable lab program and that I can contribute to its missions of waste reduction and decreasing our carbon footprint. This program has provided opportunities to recycle lab supplies, share equipment, and reuse chemicals. We only have one planet and we need to all we can to protect it.” Marin Klumpner, Lab Manager
Pennathur Laboratory Brehm 5450
Our research focused on the applications of biological mass spectrometry in disease pathogenesis. A major focus of the lab has been to define the role of oxidative stress on disease pathogenesis and complications. We have utilized mass spectrometry to identify key protein and metabolite alterations in disease states and tested the hypothesis whether these alterations predict complications in animal models and humans. Our strategy has been to develop analytical techniques in animal models and validate these markers in humans and then interrogating the animal model for biological pathway relevance. Recent extension of this work has included targeted as well as unbiased metabolomic and proteomic profiling. Waste generated in our lab is disposed of using OSEH guidelines.
“This program has helped us identify many new ways to operate sustainably. We're able to recycle much more, both chemicals and waste, and reduce our energy use, using the info provided by the program. Everyone in the lab is motivated to function as sustainably as possible, and the Sustainable Lab program has been integral to our efforts.”
-- Nancy Roeser, Lab Manager
Tropical Climbing Plants Laboratory Ruthven 1047
Our research involves morphological analysis of climbing plant species, seed germination, stem re-sprouting/re-rooting capability trials, and computer analysis of all data. Our specimens come from Amazonian Ecuador, Peru, and Brazil where we carry out biodiversity and ecological research on the dominant species of moist tropical forest. Specimens are dried using standard drying ovens and plant presses, and housed in sealed herbarium cabinets. Waste is rarely generated in our lab. Rare solid and liquid waste generated in our lab is disposed of adhering to U-M OSEH guidelines.
“The Sustainable Lab program staff were very helpful with respect to increasing our awareness of safe and sustainable lab practices and evaluating our current use of resources. With their assistance we have updated our energy use to eliminate connections that are not needed, and we have eliminated mercury thermometers in the lab. We have also updated our recycling practices and posted signs about recycling and composting in the lab. We are committed to purchasing eco-friendly products whenever possible. These changes were very easy to adopt, and we are happy to participate in this program and help U-M reach its campus-wide sustainability goals.”
-- Prof. Robyn Burnham, PI
Montgomery Laboratory Chemistry 3724-3728
Our research focuses on the discovery of new transition metal-catalyzed reactions, the development of useful synthetic methods, the application of these new reactions in complex molecule synthesis, and mechanistic studies designed to understand the new processes developed in our laboratories. Common equipment used on a daily basis include NMR, MS, GC/MS, GC/FID, HPLC, gloveboxes, rotary evaporators, kugelrohr, Biotage automated chromatography, and vacuum lines. Common techniques include reaction set-up, chromatography, distillations, extractions and spectroscopic analysis. Solid and hazardous waste generated in our lab is disposed of adhering to U-M OSEH guidelines.
“We are very happy to participate in the Sustainable Lab program to work towards making our lab more eco-friendly. Now more than ever we are dedicated to using green chemistry practices and reducing energy consumption whenever possible to make sure that we do our part in helping our environment. We highly encourage other laboratories at Michigan to take advantage of this opportunity and to be a part of planet blue!”
-- Jessica Stachowski, Lab Manager
Denver Laboratory Kraus 3071, 3077
We study hormone action during animal development, with emphasis on the nervous system. Our molecular and cellular studies are integrated with organismic level questions of physiological adaptation to environmental change and the evolution of vertebrate neuroendocrine systems.Waste generated in our lab is disposed of using OSEH guidelines.
“Denver lab is very happy to be the part of Sustainable Lab program. We eliminated the use of ethidium bromide by making use of safer alternatives. We now recycle all empty pipette tip boxes and clean media bottles. The Chemical Reuse program has us allowed us to procure chemicals, etc. at no cost. We also keep equipment that is not being used daily unplugged. This is a great program.”
-- Arasakumar Subramani, Lab Manager
Penner-Hahn Laboratory Chemistry Rooms 4205, 4213, 4208, & 4211
Our group is interested in the spectroscopic investigation of metal site structure in bioinorganic systems. We focus our studies in understanding the detailed mechanism of enzymes with Zn as an active site. It is estimated that as many as one-third of all proteins are metalloproteins. We are engaged in attempting to identify and characterize the metal bonding sites in these proteins. We develop new techniques in X-Ray spectroscopy to determine the local side structure of metals ions in the biological systems. Our research also involves studying the distribution of metals in red blood cells infected with malaria and the distribution of metals in the hippocampus. We do not generate hazardous waste. Other solid waste generated is recycled or disposed of as trash.
“Using the Sustainable Lab program has been highly beneficial to our lab. We powered down many equipment that is not being used on a regular basis. Many recycling programs have been initiated as part of this program. We are glad that our lab is recognized through this unique program.”
-- Dr. Aniruddha Deb, Lab Manager
O'Brien Laboratory 4200 MSRB III
Our research interests focus on elucidating the catalytic mechanisms of proteins involved in DNA repair, with current focus on ligases and alkylation repair pathways. We employ a variety of electrophoresis and fluorescence techniques in addition to mutation assays in biological systems. Waste generated in our lab is disposed of adhering to OSEH guidelines.
Participation in the Sustainable Lab Recognition Program has improved our awareness of the environmental impact of our research. It has helped us to develop energy-saving practices, reduced our hazardous waste generation, and introduced us to various recycling streams. Michael Baldwin, lab manager