Telesnitsky Laboratory MS II Room 6714
Our lab studies the interplay of cellular RNA trafficking and retroviral replication steps as well as mechanisms of HIV-1 and other retroviral genetic variation. We use a number of genetic, molecular and biological techniques, such as PCR, gel electrophoresis, western blot, northern blot, cellular transformation, and transfection. We began using Gel Red as a safer product to replace toxic ethidium bromide in gel work. We’ve also utilized various recycling opportunities supplied by the Sustainable Lab Program. Waste generated in our lab is disposed of adhering to OSEH guidelines.
“I am so glad that the University of Michigan has a sustainable lab program. Our university is a leader in so many areas and I’m glad sustainability is one of them. The sharing of resources (like equipment), transitioning to less toxic reagents, and recycling alternatives to traditional waste streams are all wonderful improvement on the laboratory practices used in the past.
Trievel Laboratory MSRB 3 Room 4315
Our laboratory uses a combination of biochemical and biophysical approaches to study the structures, mechanisms, and substrate specificities of a variety of enzymes, with a particularly focus on chromatin modifying enzymes. Techniques used in the lab include crystallography, enzyme kinetics, calorimetry, and other biophysical and biochemical approaches. Current projects include: Structural and functional studies of chromatin modifying enzymes, mechanisms of S-Adenosylmethionine dependent methyltransferaces and structure function studies for a target anti-fungal drug design. The solid and hazardous waste generated from our lab is being disposed of adhering to U-M EHS guidelines.
“We are happy to participate in the Sustainable Lab program, and we have taken steps to create a safer and more sustainable laboratory environment. We recycle waste when appropriate, purchase eco-friendly products, and turn off and unplug unused devices to reduce energy consumption. By participating in various campus reuse programs, we try to re-use reagents, materials, and equipment before purchasing new ones. We are glad to contribute to U-M’s campus-wide goals to improve up on sustainability” –Prof. Raymond Trievel, Principal Investigator.
Arvan Laboratory Brehm Room 5410
The central focus of our lab is to examine molecular mechanisms involved in the trafficking and selective targeting of newly synthesized endocrine secretory proteins. Specifically we are interested in understanding the biology of secretory pathway defects that lead to diabetes and hypothyroidism, respectively, using cell culture and animal models. The solid and hazardous waste generated from our lab is being disposed of adhering to U-M EHS guidelines.
“We are happy to participate in the Sustainable Lab program, and we have taken steps to create a safer and more sustainable laboratory environment. We recycle waste when appropriate, purchase eco-friendly products, and turn off and unplug unused devices to reduce energy consumption. By participating in various campus reuse programs, we try to re-use reagents, materials, and equipment before purchasing new ones. We are glad to contribute to U-M’s campus-wide goals to improve up on sustainability”
-- Dennis Larkin, Lab Manager
Orthotics & Prosthetics Center
UMOPC lab fabricates custom orthotic and prosthetic devices for our patients. Fabrication involves thermoforming foam and plastic as well as laminating carbon fiber, nylon and fiberglass. Cutting, grinding and buffing ultimately produce quality custom devices.
Solid and hazardous waste generated in our lab is disposed of adhering to EHS guidelines. We recycle or reuse: paper, packaging, packing material, cardboard and plastic.
“Reduce, reuse, and recycle are goals in my daily life. I am glad that I can help to promote and implement these practices in our department by joining the Sustainable Lab Program. Thanks to the program we are now recycling 40lbs of plastic each week! We are well on our way to becoming an environmentally friendly department. We are proud to share the success and plan to continue with the program to become sustainability ambassadors for our department, university, community and planet”. Jill Petkash, Purchasing Manager
Hughes Laboratory Kellogg Eye Center Room 325
Our lab studies ion channels in the retinal pigment epithelium. We use electrophysiology, cell culture, immunofluorescence microscopy, PCR, Western blotting, and recombinant DNA techniques. Liquid and solid hazardous waste generated in our lab is manifested and disposed of adhering to EHS guidelines.
“We are thankful for the information provided by the Sustainable Lab program that has enabled us to recycle more, to reduce hazardous material use, and reduce our energy use. This program has helped us find new ways and encouraged our lab to function as sustainably as possible.” -- Melissa Bajcz, Lab Manager
Farkash Laboratory MSRB I Room A526
Our research studies factors that affect long term graft survival and patient outcomes after transplantation, specifically antibody mediated rejection (in which the immune system generates antibodies that recognize the donor kidney, causes direct or indirect endothelial injury, and recruit inflammation). Another area of study is the relationship between BK polyomavirus and urinary tract cancers. BK can reactivate in kidney and bone marrow transplant recipients and cause severe kidney and bladder infections. We employ techniques such as PCR, IHC, and IF. We dispose of our waste following EHS guidelines.
“Being enrolled in the Sustainable Lab program has educated us on many ways we can reduce our waste and harmful reagents. We do not use ethidium bromide and also recycle waste and empty containers. Our lab has also had the pleasure of using the Chemical Reuse program, as it has allowed us the option to reuse materials instead of buying new.”
-- Jenna Barnes, Lab Manager
Reddy Laboratory Cancer Center Rooms 3110, 3120, 3130
Our lab studies graph vs. host disease (GVHD) that occurs in patients after bone marrow and organ transplants. We use mouse models to study GVHD by performing BM transplants and studying results based on manipulation of the T cells. We use cell culture for in vitro studies and use radio-isotopes for functional assays of the T cells. Techniques/equipment used are: BSC’s, centrifuges, incubators, PCR, etc., Hazardous and non-hazardous waste generated in our lab is disposed of adhering to U-M EHS guidelines.
In our small way, we have always tried to recycle as much as we could. But not until we heard from the Sustainability Lab Program, did we understand how much more we could be doing. Our whole lab has become committed to all aspects of the program of “reduce, reuse and recycle”. Our initiation of Styrofoam recycling with a central location has enabled other labs on our floor to join us in this effort. I would encourage everyone to participate in this program.
Katherine Oravecz-Wilson, Manager
Amidon Laboratory Pharmacy Rooms 4009 & 4025
In our work bioinformatic tools have been used for the identification of new targets for anti-cancer prodrug delivery. This will mark a new era in the drug absorption, transport and delivery, a beginning for molecular biopharmaceutics. The information available in our lab expression databases in addition to public information is skimmed using various software tools to shortlist possible targets and various studies done to understand the feasibility of those targets for prodrug delivery. The microarray and Genechip data provide powerful information for designing prodrug targeting strategies. We use HPLC for separation and purification of target compounds. Waste generated in our lab is disposed of using OSEH guidelines.
“Participating in the Sustainable Lab program has proven to be highly beneficial to our lab. We initiated a few recycling programs and took action to conserve energy. PIAB systems are helping us save on water consumption. The Chemical Reuse program has us allowed us to procure chemicals, etc. at no cost. This is a great program. Thank you OCS.S”
-- Hiro Tsume, Lab Manager
Burmeister Laboratory BSRB Room 5488
Our lab validates exome sequencing data by PCR and Sanger Sequencing with the goal of identifying novel ataxia genes. We collect whole blood from subjects and genotype for behavioral related variants. We also receive primary tissue samples such as whole blood and saliva and extract DNA from these tissues. We biopsy skin from patients, use episomal plasmids to reprogram cultured patient specific fibroblasts into iPSCs, and differentiate these into neurons. Waste generated in the lab is disposed of adhering to EHS guidelines.
Being a responsible laboratory is important as waste streams generated can often be harmful to the environment if not handled and disposed of properly. We continually strive to seek out and implement more environmentally friendly alternatives. It’s exciting that the Burmeister lab is now one of the many sustainable labs at the University of Michigan following the University's sustainability guidelines. We are very proud to say we are ambassadors of U of M, Planet Blue. Linda Gates, Manager
Cornell Laboratory BSRB Rooms 4468
Our work focuses on immunology and cell signaling research using the following techniques: genotyping, western blotting, immunoprecipitation, cell culture – including work with endotoxins, flow cytometry, mouse surgery, blood draws (humans and mice), work with adeno – and retroviruses, cell transfection, RNA/DNA/Protein extraction. We employ flow cytometer, PCR, qPCR, gel documentation system, centrifuges, QIAcube etc. in our work. Hazardous and non-hazardous waste generated in our lab is disposed of adhering to U-M EHS guidelines.
“Reduce, reuse, and recycle” should be goals for everyone in daily life. Joining the Sustainable Lab Program has given us a platform to promote and implement these practices in Cornell Laboratory. We have learned more strategies of becoming an environmentally friendly research lab and strongly recommend to others. Kelli McDonough, Manager